查看文章

Hypoxia is defined as any combination of reduced barometric pressure (PB) and/or a reduced inspired fraction of oxygen (FIO2), which ultimately results in an inspired partial pressure of oxygen (PIO2) less than 150 mmHg (6). Pathophysiological responses to hypoxia or adaptations to hypoxic training can be investigated in two different types of exposure: hypobaric hypoxia (HH; FIO2 20.9%; PB 760 mmHg) or normobaric hypoxia (NH; FIO2 20%; PB 760 mmHg). Traditionally, the decrease in PIO2 was thought to be the only factor relating to the physiological responses to hypoxia. Therefore, any combination of reduced PB and FIO2 resulting in the same PIO2 would potentially produce the same physiological response. This hypothesis suggests that HH and NH can be used interchangeably, both in medicine and in sport. However, a growing body of evidence in various scientific areas such as ventilation (17, 25, 29 …