作者
Devin Razavi-Shearer, Ivane Gamkrelidze, Mindie H Nguyen, Ding-Shinn Chen, Pierre Van Damme, Zaigham Abbas, Maheeba Abdulla, Antoine Abou Rached, Danjuma Adda, Inka Aho, Ulus Akarca, Fuad Hasan, Faryal Al Lawati, Khalid Al Naamani, Hamad Ibrahim Al-Ashgar, Seyed M Alavian, Sameer Alawadhi, Agustin Albillos, Said A Al-Busafi, Soo Aleman, Faleh Z Alfaleh, Abdulrahman A Aljumah, Anil C Anand, Nguyen Thu Anh, Joop E Arends, Perttu Arkkila, Kostas Athanasakis, Abate Bane, Ziv Ben-Ari, Thomas Berg, Abdul R Bizri, Sarah Blach, Carlos E Brandão Mello, Samantha M Brandon, Bisi Bright, Philip Bruggmann, Maurizia Brunetto, Maria Buti, Henry LY Chan, Asad Chaudhry, Rong-Nan Chien, Moon S Choi, Peer B Christensen, Wan-Long Chuang, Vladimir Chulanov, Mette R Clausen, Massimo Colombo, Markus Cornberg, Benjamin Cowie, Antonio Craxi, Esther A Croes, Diego Alberto Cuellar, Chris Cunningham, Hailemichael Desalegn, Sylvia Drazilova, Ann-Sofi Duberg, Steve S Egeonu, Manal H El-Sayed, Chris Estes, Karolin Falconer, Maria LG Ferraz, Paulo R Ferreira, Robert Flisiak, Sona Frankova, Giovanni B Gaeta, Javier García-Samaniego, Jordan Genov, Jan Gerstoft, Adrian Goldis, Ilias Gountas, Richard Gray, Mário Guimarães Pessôa, Behzad Hajarizadeh, Angelos Hatzakis, Christophe Hézode, Sayed M Himatt, Andy Hoepelman, Irena Hrstic, Yee-Tak T Hui, Petr Husa, Rohani Jahis, Naveed Z Janjua, Peter Jarčuška, Jerzy Jaroszewicz, Sabahattin Kaymakoglu, David Kershenobich, Loreta A Kondili, Aliya Konysbekova, Mel Krajden, Pavol Kristian, Wim Laleman, C Lao Wai-cheung, Jen Layden, Jeffrey V Lazarus, Mei-Hsuan Lee, Valentina Liakina, Young-Suk S Lim, K Loo Ching-kong, Boris Lukšić, Reza Malekzadeh, Abraham O Malu, Adkhamjon Mamatkulov, Michael Manns, Rui T Marinho, Mojca Maticic, Stefan Mauss, Muhammad S Memon, Maria C Mendes Correa, Nahum Mendez-Sanchez, Shahin Merat, Ammal M Metwally, Rosmawati Mohamed, Jacques E Mokhbat, Christophe Moreno, Joel Mossong, Fadi H Mourad, Beat Müllhaupt, Kimberly Murphy, Erkin Musabaev, Arif Nawaz, Helen M Nde, Francesco Negro, Alexander Nersesov, Richard Njouom, Renovat Ntagirabiri, Zuridin Nurmatov, Solomon Obekpa, Ponsiano Ocama, Stephen Oguche, Ogu Omede, Casimir Omuemu, Ohene Opare-Sem, Christopher K Opio, Necati Örmeci, George Papatheodoridis, Ken Pasini, Nikolay Pimenov, Hossein Poustchi, Trân D Quang, Huma Qureshi, Alnoor Ramji, Kathryn Razavi-Shearer, Berhane Redae, Henk W Reesink, Cielo Yaneth Rios, Gabriela Rjaskova, Sarah Robbins, Lewis R Roberts, Stuart K Roberts, Stephen D Ryder
发表日期
2018/6/1
来源
The lancet Gastroenterology & hepatology
卷号
3
期号
6
页码范围
383-403
出版商
Elsevier
简介
Background
The 69th World Health Assembly approved the Global Health Sector Strategy to eliminate viral hepatitis by 2030. Although no virological cure exists for hepatitis B virus (HBV) infection, existing therapies to control viral replication and prophylaxis to minimise mother-to-child transmission make elimination of HBV feasible. We aimed to estimate the national, regional, and global prevalence of HBsAg in the general population and in the population aged 5 years in 2016, as well as coverage of prophylaxis, diagnosis, and treatment.
Methods
In this modelling study, we used a Delphi process that included a literature review in PubMed and Embase, followed by interviews with experts, to quantify the historical epidemiology of HBV infection. We then used a dynamic HBV transmission and progression model to estimate the country-level and regional-level prevalence of HBsAg in 2016 and the effect of prophylaxis …
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