作者
Jürgen Rehm, Andriy V Samokhvalov, Manuela G Neuman, Robin Room, Charles Parry, Knut Lönnroth, Jayadeep Patra, Vladimir Poznyak, Svetlana Popova
发表日期
2009/12
来源
BMC public health
卷号
9
页码范围
1-12
出版商
BioMed Central
简介
Background
In 2004, tuberculosis (TB) was responsible for 2.5% of global mortality (among men 3.1%; among women 1.8%) and 2.2% of global burden of disease (men 2.7%; women 1.7%). The present work portrays accumulated evidence on the association between alcohol consumption and TB with the aim to clarify the nature of the relationship.
Methods
A systematic review of existing scientific data on the association between alcohol consumption and TB, and on studies relevant for clarification of causality was undertaken.
Results
There is a strong association between heavy alcohol use/alcohol use disorders (AUD) and TB. A meta-analysis on the risk of TB for these factors yielded a pooled relative risk of 2.94 (95% CI: 1.89-4.59). Numerous studies show pathogenic impact of alcohol on the immune system causing …
引用总数
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J Rehm, AV Samokhvalov, MG Neuman, R Room… - BMC public health, 2009