作者
Todd C Villines, Edward A Hulten, Leslee J Shaw, Manju Goyal, Allison Dunning, Stephan Achenbach, Mouaz Al-Mallah, Daniel S Berman, Matthew J Budoff, Filippo Cademartiri, Tracy Q Callister, Hyuk-Jae Chang, Victor Y Cheng, Kavitha Chinnaiyan, Benjamin JW Chow, Augustin Delago, Martin Hadamitzky, Jörg Hausleiter, Philipp Kaufmann, Fay Y Lin, Erica Maffei, Gilbert L Raff, James K Min, CONFIRM Registry Investigators
发表日期
2011/12/6
期刊
Journal of the American College of Cardiology
卷号
58
期号
24
页码范围
2533-2540
出版商
American College of Cardiology Foundation
简介
Objectives
The purpose of this study was to describe the prevalence and severity of coronary artery disease (CAD) in relation to prognosis in symptomatic patients without coronary artery calcification (CAC) undergoing coronary computed tomography angiography (CCTA).
Background
The frequency and clinical relevance of CAD in patients without CAC are unclear.
Methods
We identified 10,037 symptomatic patients without CAD who underwent concomitant CCTA and CAC scoring. CAD was assessed as <50%, ≥50%, and ≥70% stenosis. All-cause mortality and the composite endpoint of mortality, myocardial infarction, or late coronary revascularization (≥90 days after CCTA) were assessed.
Results
Mean age was 57 years, 56% were men, and 51% had a CAC score of 0. Among patients with a CAC score of 0, 84% had no CAD, 13% had nonobstructive stenosis, and 3.5% had ≥50% stenosis (1.4% had ≥70 …
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TC Villines, EA Hulten, LJ Shaw, M Goyal, A Dunning… - Journal of the American College of Cardiology, 2011