作者
Martin Hadamitzky, Stephan Achenbach, Mouaz Al-Mallah, Daniel Berman, Matthew Budoff, Filippo Cademartiri, Tracy Callister, Hyuk-Jae Chang, Victor Cheng, Kavitha Chinnaiyan, Benjamin JW Chow, Ricardo Cury, Augustin Delago, Allison Dunning, Gudrun Feuchtner, Millie Gomez, Philipp Kaufmann, Yong-Jin Kim, Jonathon Leipsic, Fay Y Lin, Erica Maffei, James K Min, Gil Raff, Leslee J Shaw, Todd C Villines, Jörg Hausleiter, CONFIRM Investigators
发表日期
2013/7/30
期刊
Journal of the American College of Cardiology
卷号
62
期号
5
页码范围
468-476
出版商
American College of Cardiology Foundation
简介
Objectives
The aim of this study was to analyze the predictive value of coronary computed tomography angiography (CCTA) and to model and validate an optimized score for prognosis of 2-year survival on the basis of a patient population with suspected coronary artery disease (CAD).
Background
Coronary computed tomography angiography carries important prognostic information in addition to the detection of obstructive CAD. But it is still unclear how the results of CCTA should be interpreted in the context of clinical risk predictors.
Methods
The analysis is based on a test sample of 17,793 patients and a validation sample of 2,506 patients, all with suspected CAD, from the international CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) registry. On the basis of CCTA data and clinical risk scores, an optimized score was modeled. The endpoint was all-cause …
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