作者
James K Min, Allison Dunning, Fay Y Lin, Stephan Achenbach, Mouaz Al-Mallah, Matthew J Budoff, Filippo Cademartiri, Tracy Q Callister, Hyuk-Jae Chang, Victor Cheng, Kavitha Chinnaiyan, Benjamin JW Chow, Augustin Delago, Martin Hadamitzky, Joerg Hausleiter, Philipp Kaufmann, Erica Maffei, Gilbert Raff, Leslee J Shaw, Todd Villines, Daniel S Berman, CONFIRM Investigators
发表日期
2011/8/16
期刊
Journal of the American College of Cardiology
卷号
58
期号
8
页码范围
849-860
出版商
American College of Cardiology Foundation
简介
Objectives
We examined mortality in relation to coronary artery disease (CAD) as assessed by ≥64-detector row coronary computed tomography angiography (CCTA).
Background
Although CCTA has demonstrated high diagnostic performance for detection and exclusion of obstructive CAD, the prognostic findings of CAD by CCTA have not, to date, been examined for age- and sex-specific outcomes.
Methods
We evaluated a consecutive cohort of 24,775 patients undergoing ≥64-detector row CCTA between 2005 and 2009 without known CAD who met inclusion criteria. In these patients, CAD by CCTA was defined as none (0% stenosis), mild (1% to 49% stenosis), moderate (50% to 69% stenosis), or severe (≥70% stenosis). CAD severity was judged on a per-patient, per-vessel, and per-segment basis. Time to mortality was estimated using multivariable Cox proportional hazards models.
Results
At a 2.3 ± 1.1-year …
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JK Min, A Dunning, FY Lin, S Achenbach, M Al-Mallah… - Journal of the American College of Cardiology, 2011