作者
Victor Y Cheng, Daniel S Berman, Alan Rozanski, Allison M Dunning, Stephan Achenbach, Mouaz Al-Mallah, Matthew J Budoff, Filippo Cademartiri, Tracy Q Callister, Hyuk-Jae Chang, Kavitha Chinnaiyan, Benjamin JW Chow, Augustin Delago, Millie Gomez, Martin Hadamitzky, Jörg Hausleiter, Ronald P Karlsberg, Philipp Kaufmann, Fay Y Lin, Erica Maffei, Gilbert L Raff, Todd C Villines, Leslee J Shaw, James K Min
发表日期
2011/11/29
期刊
Circulation
卷号
124
期号
22
页码范围
2423-2432
出版商
Lippincott Williams & Wilkins
简介
Background
Guidelines for the management of patients with suspected coronary artery disease (CAD) rely on the age, sex, and angina typicality–based pretest probabilities of angiographically significant CAD derived from invasive coronary angiography (guideline probabilities). Reliability of guideline probabilities has not been investigated in patients referred to noninvasive CAD testing.
Methods and Results
We identified 14048 consecutive patients with suspected CAD who underwent coronary computed tomographic angiography. Angina typicality was recorded with the use of accepted criteria. Pretest likelihoods of CAD with ≥50 diameter stenosis (CAD50) and ≥70 diameter stenosis (CAD70) were calculated from guideline probabilities. Computed tomographic angiography images were evaluated by ≥1 expert reader to determine the presence of CAD50 and CAD70. Typical angina was associated with the …
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