作者
Ebenezer T Oni, Arthur S Agatston, Michael J Blaha, Jonathan Fialkow, Ricardo Cury, Andrei Sposito, Raimund Erbel, Ron Blankstein, Ted Feldman, Mouaz H Al-Mallah, Raul D Santos, Matthew J Budoff, Khurram Nasir
发表日期
2013/10/1
来源
Atherosclerosis
卷号
230
期号
2
页码范围
258-267
出版商
Elsevier
简介
Background
Non-alcoholic fatty liver disease (NAFLD) is an emerging disease and a leading cause of chronic liver disease. The prevalence in the general population is approximately 15–30% and it increases to 70–90% in obese or diabetic populations. NAFLD has been linked to increased cardiovascular disease (CVD) risk. It is therefore critical to evaluate the relationship between markers of subclinical CVD and NAFLD.
Method
An extensive search of databases; including the National Library of Medicine and other relevant databases for research articles meeting inclusion criteria: observational or cohort, studies in adult populations and clearly defined NAFLD and markers of subclinical CVD.
Results
Twenty-seven studies were included in the review; 16 (59%) presented the association of NAFLD and carotid intima-media thickness (CIMT), 7 (26%) the association with coronary calcification and 7 (26%) the effect on …
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