作者
Jila Yavarian, Somaye Shatizadeh Malekshahi, Roya Yavarian, Shaghayegh Yazdani, Leila Janani, Nazanin Zahra Shafiei Jandaghi, Seyed Jalal Kiani, HamidReza Ahamadkhaniha
发表日期
2015/12
期刊
BMC psychiatry
卷号
15
页码范围
1-6
出版商
BioMed Central
简介
Background
Schizophrenia (SC) and bipolar disorder (BD) are among the most devastating diseases worldwide. There are several lines of evidence suggesting that viruses may play significant roles in the etiology of these mental disorders. The aim of this study was the detection of HHV-6A/B in the peripheral blood mononuclear cells (PBMC) of SC and BD patients versus the healthy control (HC) subjects using a new method of type-specific Real time PCR analysis.
Methods
A type-specific Real time PCR was performed for simultaneous detection and typing of HHV-6A/B in the PBMCs of 120 SC and BD patients and 75 HCs.
Results
Only one case of HHV-6B out of 120 (0.8 %) SC and BD patients and two cases of HHV-6A (2.7 %) in 75 HCs were detected.
Conclusions
The low levels of …
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J Yavarian, S Shatizadeh Malekshahi, R Yavarian… - BMC psychiatry, 2015