作者
Graham A Colditz, Walter C Willett, Andrea Rotnitzky, JoAnn E Manson
发表日期
1995/4/1
期刊
Annals of internal medicine
卷号
122
期号
7
页码范围
481-486
出版商
American College of Physicians
简介
Objective
To examine the relation between adult weight change and the risk for clinical diabetes mellitus among middle-aged women.
Design
Prospective cohort study with follow-up from 1976 to 1990.
Setting
11 U.S. states.
Participants
114 281 female registered nurses aged 30 to 55 years who did not have diagnosed diabetes mellitus, coronary heart disease, stroke, or cancer in 1976.
Outcome Measures
Non-insulin-dependent diabetes mellitus.
Results
2204 cases of diabetes were diagnosed during 1.49 million person-years of follow-up. After adjustment for age, body mass index was the dominant predictor of risk for diabetes mellitus. Risk increased with greater body mass index, and even women with average weight (body mass index, 24 …
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GA Colditz, WC Willett, A Rotnitzky, JAE Manson - Annals of internal medicine, 1995
