作者
Wen-Yi Shau, Yu-Yun Shao, Yi-Chun Yeh, Zhong-Zhe Lin, Raymond Kuo, Chih-Hung Hsu, Chiun Hsu, Ann-Lii Cheng, Mei-Shu Lai
发表日期
2012/6/1
期刊
The oncologist
卷号
17
期号
6
页码范围
856-862
出版商
Oxford University Press
简介
Background
Diabetes mellitus (DM) is closely associated with hepatocarcinogenesis. This study explores the prognostic impact of DM in patients who received curative therapy for localized hepatocellular carcinoma (HCC).
Methods
Patients who had been diagnosed with stage I or II HCC in 2003 and 2004 and received surgical resection or local ablation therapy were identified from the population-based Taiwan National Cancer Registry. Data pertaining to DM and other comorbidities were retrieved from the Taiwan National Health Insurance database. Liver cancer-specific survival (LCS), liver disease-related survival (LDS) and overall survival (OS) rates were compared between patients with and without DM. The presence of other comorbidities and tumor status were adjusted using multivariate analysis.
Results
A total of 931 patients who fulfilled the study …
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WY Shau, YY Shao, YC Yeh, ZZ Lin, R Kuo, CH Hsu… - The oncologist, 2012