作者
Susanne Hempel, Sydne J Newberry, Alicia R Maher, Zhen Wang, Jeremy NV Miles, Roberta Shanman, Breanne Johnsen, Paul G Shekelle
发表日期
2012/5/9
来源
Jama
卷号
307
期号
18
页码范围
1959-1969
出版商
American Medical Association
简介
Context
Probiotics are live microorganisms intended to confer a health benefit when consumed. One condition for which probiotics have been advocated is the diarrhea that is a common adverse effect of antibiotic use.
Objective
To evaluate the evidence for probiotic use in the prevention and treatment of antibiotic-associated diarrhea (AAD).
Data Sources
Twelve electronic databases were searched (DARE, Cochrane Library of Systematic Reviews, CENTRAL, PubMed, EMBASE, CINAHL, AMED, MANTIS, TOXLINE, ToxFILE, NTIS, and AGRICOLA) and references of included studies and reviews were screened from database inception to February 2012, without language restriction.
Study Selection
Two independent reviewers identified parallel randomized controlled trials (RCTs) of probiotics (Lactobacillus, Bifidobacterium, Saccharomyces, Streptococcus, Enterococcus, and/or Bacillus) for the prevention or treatment …
学术搜索中的文章
S Hempel, SJ Newberry, AR Maher, Z Wang, JNV Miles… - Jama, 2012