作者
Ahmed Eltayeb, Faisal Al‐Sarraj, Mona Alharbi, Raed Albiheyri, Ehab H Mattar, Isam M Abu Zeid, Thamer A Bouback, Atif Bamagoos, Vladimir N Uversky, Alberto Rubio‐Casillas, Elrashdy M Redwan
发表日期
2024/2/13
来源
Journal of Cellular Biochemistry
简介
When the SARS‐CoV‐2 virus infects humans, it leads to a condition called COVID‐19 that has a wide spectrum of clinical manifestations, from no symptoms to acute respiratory distress syndrome. The virus initiates damage by attaching to the ACE‐2 protein on the surface of endothelial cells that line the blood vessels and using these cells as hosts for replication. Reactive oxygen species levels are increased during viral replication, which leads to oxidative stress. About three‐fifths (~60%) of the people who get infected with the virus eradicate it from their body after 28 days and recover their normal activity. However, a large fraction (~40%) of the people who are infected with the virus suffer from various symptoms (anosmia and/or ageusia, fatigue, cough, myalgia, cognitive impairment, insomnia, dyspnea, and tachycardia) beyond 12 weeks and are diagnosed with a syndrome called long COVID. Long‐term clinical …
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