作者
Darach O h-Ici, Sarah Jeuthe, Thore Dietrich, Hubertus Pietsch, Gunnar Schuetz, Felix Berger, Titus Kuehne, Sebastian Kozerke, Daniel Messroghli
发表日期
2013/1/1
期刊
Journal of Cardiovascular Magnetic Resonance
卷号
15
期号
1
页码范围
1-2
出版商
BioMed Central
简介
Background
Myocardial ischemia causes local edema. This has traditionally been studied using unenhanced T2-weighted MR imaging and contrast agent kinetic techniques. The aim was to study the acute T1 changes in-vivo in a novel closed chest animal model of myocardial ischemia.
Methods
8 rats had an inflatable balloon coronary occluder surgically inserted via thoracotomy. They were allowed to recover for 10-14 days. MRI was performed to obtain baseline measurement of ventricular function. T1 mapping was performed using the Small-Animal Look-Locker Inversion Recovery (SALLI) technique.
学术搜索中的文章
DO h-Ici, S Jeuthe, T Dietrich, H Pietsch, G Schuetz… - Journal of Cardiovascular Magnetic Resonance, 2013