作者
Riccardo Pampena, Tamara Palmieri, Athanassios Kyrgidis, Dafne Ramundo, Cinzia Iotti, Aimilios Lallas, Elvira Moscarella, Stefania Borsari, Giuseppe Argenziano, Caterina Longo
发表日期
2016/2/1
期刊
Journal of the American Academy of Dermatology
卷号
74
期号
2
页码范围
341-347
出版商
Mosby
简介
Background
Radiotherapy is an established treatment for some types of patients with nonmelanoma skin cancer. A hypofractionated schedule has been proposed as a valuable option for elderly disabled patients to minimize the number of hospital visits.
Objective
We sought to compare a weekly hypofractionated orthovoltage radiotherapy regimen with a standard daily one for the treatment of nonmelanoma skin cancer.
Methods
A retrospective cohort study was performed on 436 tumors. Overall survival, disease-free survival, and cosmetic outcome were measured. Life-table analysis, Kaplan-Meier survival analysis, and multivariate Cox regression model were performed.
Results
The hypofractionated regimen was not associated with increased recurrence rates and mortality, or with a poorer cosmetic outcome, when compared with the daily schedule.
Limitations
Absence of complete information about acute treatment …
学术搜索中的文章
R Pampena, T Palmieri, A Kyrgidis, D Ramundo, C Iotti… - Journal of the American Academy of Dermatology, 2016