作者
Mary Wandia Kivata, Margaret Mbuchi, Fredrick Eyase, Wallace Dimbuson Bulimo, Cecilia Katunge Kyanya, Valerie Oundo, Wilton Mwema Mbinda, Willy Sang, Ben Andagalu, Olusegun O Soge, Raymond Scott McClelland, John Distelhorst
发表日期
2020/12
期刊
BMC Infectious Diseases
卷号
20
页码范围
1-11
出版商
BioMed Central
简介
Background
Treatment of gonorrhea is complicated by the development of antimicrobial resistance in Neisseria gonorrhoeae (GC) to the antibiotics recommended for treatment. Knowledge on types of plasmids and the antibiotic resistance genes they harbor is useful in monitoring the emergence and spread of bacterial antibiotic resistance. In Kenya, studies on gonococcal antimicrobial resistance are few and data on plasmid mediated drug resistance is limited. The present study characterizes plasmid mediated resistance in N. gonorrhoeae isolates recovered from Kenya between 2013 and 2018.
Methods
DNA was extracted from 36 sub-cultured GC isolates exhibiting varying drug resistance profiles. Whole genome sequencing was done on Illumina MiSeq platform and reads assembled de-novo using CLC Genomics Workbench. Genome annotation …
学术搜索中的文章
MW Kivata, M Mbuchi, F Eyase, WD Bulimo… - BMC Infectious Diseases, 2020
