查看文章

Background: Patterns and predictors of maternal folic acid supplement use have not been examined in large prospective studies of pregnant women.

Objective: We examined the patterns and predictors of maternal folic acid supplement use from 2 mo before pregnancy through the eighth month of pregnancy.

Design: Data from 22 500 women in the Norwegian Mother and Child Cohort Study with deliveries recorded in 2000–2003 were analyzed.

Results: Folic acid supplement use increased from 11.8% at 2 mo before pregnancy to 46.9% at gestational month 3, but decreased to 26.0% at gestational month 8. Of 16 116 women (71.6%) who had taken folic acid supplements at some time before or during pregnancy, 72.4% had started use after becoming pregnant. Ten percent of the women had used supplements regularly from 1 mo before pregnancy throughout the first trimester. These women more frequently …