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Occurrence of obesity and its associated metabolic disorders continues to escalate. The present study evaluates the antiobesity effects of ethanolic fruit extract of Terminalia chebula (EETC) on high fat diet induced obese mice. The bioactive compounds present in the EETC is evaluated by Fouriertransform infrared (FTIR), Gas chromatographymass spectrometry (GCMS), and Liquid chromatographymass spectrometry (LCMS) analysis. The effects of EETC on energy intake, glucose tolerance, and various biochemical parameters were analyzed using laboratory mice. Relative gene expression of Fatty acid synthase (FAS), Peroxisome proliferatoractivated receptors α (PPARα), Carnitine palmitoyltransferase1 (CPT1), Tumor necrosis factor alpha (TNF螃) as well as Interleukin 6 (IL6) were analyzed in liver and adipose tissues. The findings reveal the hypolipidemic and antiobesity potential of EETC on …