作者
Veronika Opletalová, Asmita Patel, Michael Boulton, Alice Dundrová, Eva Lacinová, Marta Převorová, Martina Appeltauerová, Milada Coufalová
发表日期
1996
期刊
Collection of Czechoslovak chemical communications
卷号
61
期号
7
页码范围
1093-1101
出版商
Institute of Organic Chemistry and Biochemistry AS CR, vvi
简介
2-Pyrazinecarbonitrile, 2-acetylpyrazine, 5-alkyl-2-pyrazinecarboxamides, 5-alkyl-2-pyrazinecarbonitriles and 5-alkyl-2-acetylpyrazines were prepared as intermediates for use in synthesis of potential antiinflammatory agents. The results of the homolytic alkylation of pyrazinecarboxamide were compared with published data. 2-Acetylpyrazine and its 5-(1,1-dimethylethyl) derivative were screened for biological activity, but no interesting effect was found.
引用总数
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V Opletalová, A Patel, M Boulton, A Dundrová… - Collection of Czechoslovak chemical communications, 1996