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X‐ray scatter results in a significant degradation of image quality in computed tomography (CT), representing a major limitation in cone‐beam CT (CBCT) and large field‐of‐view diagnostic scanners. In this work, a novel scatter estimation and correction technique is proposed that utilizes peripheral detection of scatter during the patient scan to simultaneously acquire image and patient‐specific scatter information in a single scan, and in conjunction with a proposed compressed sensing scatter recovery technique to reconstruct and correct for the patient‐specific scatter in the projection space.

The method consists of the detection of patient scatter at the edges of the field of view (FOV) followed by measurement based compressed sensing recovery of the scatter through‐out the projection space. In the prototype implementation, the kV x‐ray source of the Varian TrueBeam OBI system was blocked …