作者
J Joukje Siebenga, Harry Vennema, Du-Ping Zheng, Jan Vinjé, Bonita E Lee, Xiao-Li Pang, Eric CM Ho, Wilina Lim, Avinash Choudekar, Shobha Broor, Tamar Halperin, Nassar BG Rasool, Joanne Hewitt, Gail E Greening, Miao Jin, Zhao-Jun Duan, Yalda Lucero, Miguel O’Ryan, Marina Hoehne, Eckart Schreier, Rodney M Ratcliff, Peter A White, Nobuhiro Iritani, Gábor Reuter, Marion Koopmans
发表日期
2009/9/1
期刊
The Journal of infectious diseases
卷号
200
期号
5
页码范围
802-812
出版商
The University of Chicago Press
简介
BackgroundNoroviruses (NoVs) are the most common cause of viral gastroenteritis. Their high incidence and importance in health care facilities result in a great impact on public health. Studies from around the world describing increasing prevalence have been difficult to compare because of differing nomenclatures for variants of the dominant genotype, GII.4. We studied the global patterns of GII.4 epidemiology in relation to its genetic diversity
MethodsData from NoV outbreaks with dates of onset from January 2001 through March 2007 were collected from 15 institutions on 5 continents. Partial genome sequences (n=775) were collected, allowing phylogenetic comparison of data from different countries
ResultsThe 15 institutions reported 3098 GII.4 outbreaks, 62% of all reported NoV outbreaks. Eight GII.4 variants were identified. Four had a global distribution—the 1996, 2002 …
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