作者
Angela Molga, Michelle Wall, Rakchha Chhetri, Li Yan Wee, Deepak Singhal, Suzanne Edwards, Nimit Singhal, David Ross, Luen Bik To, Gillian Caughey, Sepehr Shakib, Ulrich Germing, Timothy To, Devendra Hiwase
发表日期
2020/1/1
期刊
Journal of Geriatric Oncology
卷号
11
期号
1
页码范围
114-120
出版商
Elsevier
简介
Background
Treatment of older patients with myelodysplastic syndrome (MDS) is based on disease biology and performance status. Performance status, however, does not reflect increasing co-morbidities, functional dependence or psychosocial issues in older patients.
Patients and Methods
This prospective study evaluated the burden of geriatric related health issues, assessed feasibility of “tailored” Comprehensive Geriatric Assessment (CGA), and compared treatment duration and survival in older patients with MDS and oligoblastic acute myeloid leukemia with and without deficits in CGA domains (n = 98).
Results
Although only 27 (28%) patients had an Eastern Cooperative Oncology Group score ≥2, 78% (n = 77) patients had deficits in at least one CGA domain. Deficits were spread across all CGA domains, including dependence for instrumental activity of daily living (iADL; n = 33, 34%).
Importantly …
学术搜索中的文章
A Molga, M Wall, R Chhetri, LY Wee, D Singhal… - Journal of Geriatric Oncology, 2020