作者
John Peterson Myers, Frederick S vom Saal, Benson T Akingbemi, Koji Arizono, Scott Belcher, Theo Colborn, Ibrahim Chahoud, D Andrew Crain, Francesca Farabollini, Louis J Guillette Jr, Terry Hassold, Shuk-mei Ho, Patricia A Hunt, Taisen Iguchi, Susan Jobling, Jun Kanno, Hans Laufer, Michele Marcus, John A McLachlan, Angel Nadal, Jörg Oehlmann, Nicolás Olea, Paola Palanza, Stefano Parmigiani, Beverly S Rubin, Gilbert Schoenfelder, Carlos Sonnenschein, Ana M Soto, Chris E Talsness, Julia A Taylor, Laura N Vandenberg, John G Vandenbergh, Sarah Vogel, Cheryl S Watson, Wade V Welshons, R Thomas Zoeller
发表日期
2009/3
期刊
Environmental health perspectives
卷号
117
期号
3
页码范围
309-315
出版商
National Institute of Environmental Health Sciences
简介
Background
In their safety evaluations of bisphenol A (BPA), the U.S. Food and Drug Administration (FDA) and a counterpart in Europe, the European Food Safety Authority (EFSA), have given special prominence to two industry-funded studies that adhered to standards defined by Good Laboratory Practices (GLP). These same agencies have given much less weight in risk assessments to a large number of independently replicated non-GLP studies conducted with government funding by the leading experts in various fields of science from around the world.
Objectives
We reviewed differences between industry-funded GLP studies of BPA conducted by commercial laboratories for regulatory purposes and non-GLP studies conducted in academic and government laboratories to identify hazards and molecular mechanisms mediating adverse effects. We examined the methods and results in the GLP studies that were …
引用总数
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