作者
Marcelo Silveira, Flavio Teles, Erica Melo, Valeria Borges, Filipe Miranda, Fábio Dutra, Andresa Berretta, Rodrigo Cezar, Jéssica Silva, Hayna Santos, Paulo Benigno, Rogério Passos
发表日期
2020/6/1
期刊
Nephrology Dialysis Transplantation
卷号
35
期号
Supplement_3
页码范围
gfaa142. P1574
出版商
Oxford University Press
简介
Background and Aims
End-stage chronic kidney disease is associated with the condition of chronic inflammation, impacting increased cardiovascular mortality in this specific population. Patients on hemodialysis are known to be predisposed to several factors that predispose to inflammation: dialysis membranes, central venous catheters, oxidative stress, fluid overload, sodium overload, uraemic toxins. Propolis, a natural resin produced by bees from plant materials, has anti-inflammatory, immunomodulatory, and anti-oxidant properties. The aim of this study was to evaluate the impact of Brazilian green propolis extract on inflammation in hemodialysis patients. Here we present preliminary results of the trial NCT04072341.
Method
We performed a prospective trial, open-label 9-week crossover study examining the effect of Brazilian green propolis (250mg/day, in capsules) on …
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M Silveira, F Teles, E Melo, V Borges, F Miranda… - Nephrology Dialysis Transplantation, 2020