作者
Josef S Smolen, Daniel Aletaha, Johannes WJ Bijlsma, Ferdinand C Breedveld, Dimitrios Boumpas, Gerd Burmester, Bernard Combe, Maurizio Cutolo, Maarten De Wit, Maxime Dougados, Paul Emery, Alan Gibofsky, Juan Jesus Gomez-Reino, Boulos Haraoui, Joachim Kalden, Edward C Keystone, Tore K Kvien, Iain McInnes, Emilio Martin-Mola, Carlomaurizio Montecucco, Monika Schoels, Desirée Van Der Heijde
发表日期
2010/4/1
来源
Annals of the rheumatic diseases
卷号
69
期号
4
页码范围
631-637
出版商
BMJ Publishing Group Ltd
简介
Background
Aiming at therapeutic targets has reduced the risk of organ failure in many diseases such as diabetes or hypertension. Such targets have not been defined for rheumatoid arthritis (RA).
Objective
To develop recommendations for achieving optimal therapeutic outcomes in RA.
Methods
A task force of rheumatologists and a patient developed a set of recommendations on the basis of evidence derived from a systematic literature review and expert opinion; these were subsequently discussed, amended and voted upon by >60 experts from various regions of the world in a Delphi-like procedure. Levels of evidence, strength of recommendations and levels of agreement were derived.
Results
The treat-to-target activity resulted in 10 recommendations. The treatment aim was defined as remission with low disease activity being an alternative goal in patients with long-standing disease. Regular follow-up …
引用总数
学术搜索中的文章
JS Smolen, D Aletaha, JWJ Bijlsma, FC Breedveld… - Annals of the rheumatic diseases, 2010