作者
Melanie A McWade, Constantine Paras, Lisa M White, John E Phay, Carmen C Solórzano, James T Broome, Anita Mahadevan-Jansen
发表日期
2014/12/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
99
期号
12
页码范围
4574-4580
出版商
Oxford University Press
简介
Context
The inability to accurately localize the parathyroid glands during parathyroidectomy and thyroidectomy procedures can prevent patients from achieving postoperative normocalcemia. There is a critical need for an improved intraoperative method for real-time parathyroid identification.
Objective
The objective of the study was to test the accuracy of a real-time, label-free technique that uses near-infrared (NIR) autofluorescence imaging to localize the parathyroid.
Setting
The study was conducted at the Vanderbilt University endocrine surgery center.
Subjects and Methods
Patients undergoing parathyroidectomy and/or thyroidectomy were included in this study. To validate the intrinsic fluorescence signal in parathyroid, point measurements from 110 patients were collected using NIR fluorescence spectroscopy. Fluorescence imaging …
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MA McWade, C Paras, LM White, JE Phay… - The Journal of Clinical Endocrinology & Metabolism, 2014