作者
Christopher T Rentsch, Joshua A Beckman, Laurie Tomlinson, Walid F Gellad, Charles Alcorn, Farah Kidwai-Khan, Melissa Skanderson, Evan Brittain, Joseph T King, Yuk-Lam Ho, Svetlana Eden, Suman Kundu, Michael F Lann, Robert A Greevy, P Michael Ho, Paul A Heidenreich, Daniel A Jacobson, Ian J Douglas, Janet P Tate, Stephen JW Evans, David Atkins, Amy C Justice, Matthew S Freiberg
发表日期
2021/2/11
期刊
bmj
卷号
372
出版商
British Medical Journal Publishing Group
简介
Objective
To evaluate whether early initiation of prophylactic anticoagulation compared with no anticoagulation was associated with decreased risk of death among patients admitted to hospital with coronavirus disease 2019 (covid-19) in the United States.
Design
Observational cohort study.
Setting
Nationwide cohort of patients receiving care in the Department of Veterans Affairs, a large integrated national healthcare system.
Participants
All 4297 patients admitted to hospital from 1 March to 31 July 2020 with laboratory confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and without a history of anticoagulation.
Main outcome measures
The main outcome was 30 day mortality. Secondary outcomes were inpatient mortality, initiating therapeutic anticoagulation (a proxy for clinical deterioration, including thromboembolic events), and bleeding that required transfusion.
Results
Of 4297 …
学术搜索中的文章
CT Rentsch, JA Beckman, L Tomlinson, WF Gellad… - Bmj, 2021