作者
Muhammad Adnan, Waqar Islam, Ali Noman, Ansar Hussain, Muhammad Anwar, Muhammad Umar Khan, Waheed Akram, Muhammad Furqan Ashraf, Muhammad Fahad Raza
发表日期
2020/3/1
期刊
Microbial pathogenesis
卷号
140
页码范围
103948
出版商
Academic Press
简介
SNAREs (Soluble N-ethylmaleimide-sensitive factor attachment protein receptors) help intracellular vesicle trafficking and membrane fusion among eukaryotes. They are vital for growth and development of phyto-pathogenic fungi such as Fusarium graminearum which causes Fusarium Head Blight (FHB) of wheat and barley. The SNARE protein Syn8 and its homologues play many roles among different organisms. Here, we have characterized FgSyn8 in F. graminearum as a homologue of Syn8. We have integrated biochemical, microbiological and molecular genetic approaches to investigate the roles of this protein. Our results reveal that FgSyn8 is indispensable for normal vegetative growth, conidiation, conidial morphology and pathogenicity of F. graminearum. Deoxynivalenol (DON) biochemical assay reveals active participation of this protein in DON production of F. graminearum. This has further been …
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M Adnan, W Islam, A Noman, A Hussain, M Anwar… - Microbial pathogenesis, 2020