作者
Jin Young Ahn, Je Eun Song, Min Hyung Kim, Heun Choi, Jae Kyung Kim, Hea Won Ann, Jung Ho Kim, Yongduk Jeon, Su Jin Jeong, Sun Bean Kim, Nam Su Ku, Sang Hoon Han, Young Goo Song, Dongeun Yong, Kyungwon Lee, June Myung Kim, Jun Yong Choi
发表日期
2014/6/1
期刊
American journal of infection control
卷号
42
期号
6
页码范围
621-625
出版商
Mosby
简介
Background
Carbapenem resistance among gram-negative bacilli is an emerging threat worldwide. The objective of this study was to identify risk factors for the acquisition of carbapenem-resistant Escherichia coli (CRE).
Methods
We conducted a matched case-control study comprising 57 cases of acquisition of CRE and 114 controls (1:2 matched) selected from patients with a culture of carbapenem-susceptible E coli between January 2006 and December 2010 at a 2000-bed tertiary care center in South Korea.
Results
On univariate analysis, previous use of carbapenem (P < .01), fluoroquinolone (P < .01), and glycopeptide (P < .01), as well as length of hospital stay (P < .05), were significantly associated with CRE acquisition. On multivariate analysis, previous use of carbapenem (odds ratio [OR], 4.56; 95% confidence interval [CI] 1.44-14.46; P = .01) and previous use of fluoroquinolone (OR, 2.81; 95% CI, 1.14-6.99 …
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