作者
Tomoko Nishi, Yukari Kobayashi, Jeffrey W Christle, Nicholas Cauwenberghs, Kalyani Boralkar, Kegan Moneghetti, Myriam Amsallem, Kristofer Hedman, Kévin Contrepois, Jonathan Myers, Kenneth W Mahaffey, Ingela Schnittger, Tatiana Kuznetsova, Latha Palaniappan, Francois Haddad
发表日期
2020/8/1
期刊
European Heart Journal-Cardiovascular Imaging
卷号
21
期号
8
页码范围
876-884
出版商
Oxford University Press
简介
Aims
Resting echocardiography is a valuable method for detecting subclinical heart failure (HF) in patients with diabetes mellitus (DM). However, few studies have assessed the incremental value of diastolic stress for detecting subclinical HF in this population.
Methods and results
Asymptomatic patients with Type 2 DM were prospectively enrolled. Subclinical HF was assessed using systolic dysfunction (left ventricular longitudinal strain <16% at rest and <19% after exercise in absolute value), abnormal cardiac morphology, or diastolic dysfunction (E/e′ > 10). Metabolic equivalents (METs) were calculated using treadmill speed and grade, and functional capacity was assessed by percent-predicted METs (ppMETs). Among 161 patients studied (mean age of 59 ± 11 years and 57% male sex), subclinical HF was observed in 68% at rest and in 79% with exercise. Among …
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T Nishi, Y Kobayashi, JW Christle, N Cauwenberghs… - European Heart Journal-Cardiovascular Imaging, 2020