作者
Seung-Jung Park, Jung-Min Ahn, Soo-Jin Kang, Sung-Han Yoon, Bon-Kwon Koo, Jong-Young Lee, Won-Jang Kim, Duk-Woo Park, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park
发表日期
2014/8
期刊
JACC: Cardiovascular Interventions
卷号
7
期号
8
页码范围
868-874
出版商
American College of Cardiology Foundation
简介
Objectives
This study sought to evaluate the intravascular ultrasound (IVUS) minimal lumen area (MLA) for functionally significant left main coronary artery (LMCA) stenosis using fractional flow reserve (FFR) as the standard.
Background
The evaluation of significant LMCA stenosis remains challenging.
Methods
We identified 112 patients with isolated ostial and shaft intermediate LMCA stenosis (angiographic diameter stenosis of 30% to 80%) who underwent IVUS and FFR measurement.
Results
The FFR was ≤0.80 in 66 LMCA lesions (59%); these exhibited smaller reference vessels, smaller minimal lumen diameter, greater diameter of stenosis, longer lesion length, smaller MLA, larger plaque burden, and more frequent plaque rupture. The independent factors of an FFR of ≤0.80 were plaque rupture (odds ratio [OR]: 4.47; 95% Confidence Interval (CI): 1.35 to 14.8; p = 0.014); body mass index (OR: 1.19; 95% CI: 1 …
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SJ Park, JM Ahn, SJ Kang, SH Yoon, BK Koo, JY Lee… - JACC: Cardiovascular Interventions, 2014
