作者
Seung-Jung Park, Jung-Min Ahn, Young-Hak Kim, Duk-Woo Park, Sung-Cheol Yun, Jong-Young Lee, Soo-Jin Kang, Seung-Whan Lee, Cheol Whan Lee, Seong-Wook Park, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee, David J Cohen, Alan C Yeung, Seung Ho Hur, Ki Bae Seung, Tae Hoon Ahn, Hyuck Moon Kwon, Do-Sun Lim, Seung-Woon Rha, Myung-Ho Jeong, Bong-Ki Lee, Damras Tresukosol, Guo Sheng Fu, Tiong Kiam Ong
发表日期
2015/3/26
期刊
New England Journal of Medicine
卷号
372
期号
13
页码范围
1204-1212
出版商
Massachusetts Medical Society
简介
Background
Most trials comparing percutaneous coronary intervention (PCI) with coronary-artery bypass grafting (CABG) have not made use of second-generation drug-eluting stents.
Methods
We conducted a randomized noninferiority trial at 27 centers in East Asia. We planned to randomly assign 1776 patients with multivessel coronary artery disease to PCI with everolimus-eluting stents or to CABG. The primary end point was a composite of death, myocardial infarction, or target-vessel revascularization at 2 years after randomization. Event rates during longer-term follow-up were also compared between groups.
Results
After the enrollment of 880 patients (438 patients randomly assigned to the PCI group and 442 randomly assigned to the CABG group), the study was terminated early owing to slow enrollment. At 2 years, the primary end point had occurred in 11.0% of the patients in the PCI group and in 7.9% of …
学术搜索中的文章
SJ Park, JM Ahn, YH Kim, DW Park, SC Yun, JY Lee… - New England Journal of Medicine, 2015
