作者
Seung-Jung Park, Young-Hak Kim, Duk-Woo Park, Sung-Cheol Yun, Jung-Min Ahn, Hae Geun Song, Jong-Young Lee, Won-Jang Kim, Soo-Jin Kang, Seung-Whan Lee, Cheol Whan Lee, Seong-Wook Park, Cheol-Hyun Chung, Jae-Won Lee, Do-Sun Lim, Seung-Woon Rha, Sang-Gon Lee, Hyeon-Cheol Gwon, Hyo-Soo Kim, In-Ho Chae, Yangsoo Jang, Myung-Ho Jeong, Seung-Jea Tahk, Ki Bae Seung
发表日期
2011/5/5
期刊
New England Journal of Medicine
卷号
364
期号
18
页码范围
1718-1727
出版商
Massachusetts Medical Society
简介
Background
Percutaneous coronary intervention (PCI) is increasingly used to treat unprotected left main coronary artery stenosis, although coronary-artery bypass grafting (CABG) has been considered to be the treatment of choice.
Methods
We randomly assigned patients with unprotected left main coronary artery stenosis to undergo CABG (300 patients) or PCI with sirolimus-eluting stents (300 patients). Using a wide margin for noninferiority, we compared the groups with respect to the primary composite end point of major adverse cardiac or cerebrovascular events (death from any cause, myocardial infarction, stroke, or ischemia-driven target-vessel revascularization) at 1 year. Event rates at 2 years were also compared between the two groups.
Results
The primary end point occurred in 26 patients assigned to PCI as compared with 20 patients assigned to CABG (cumulative event rate, 8.7% vs. 6.7%; absolute …
引用总数
学术搜索中的文章
SJ Park, YH Kim, DW Park, SC Yun, JM Ahn, HG Song… - New England Journal of Medicine, 2011