作者
Adriane Cristina Bovo, Priscila Grecca Pedrão, Yasmin Medeiros Guimarães, Luani Rezende Godoy, Júlio César Possati Resende, Adhemar Longatto-Filho, Ricardo Dos Reis
发表日期
2023/12
来源
Revista Brasileira de Ginecologia e Obstetrícia/RBGO Gynecology and Obstetrics
卷号
45
期号
12
页码范围
e818-e824
出版商
Thieme Revinter Publicações Ltda.
简介
Cervical cancer (CC) is caused by persistent infection of human papillomavirus of high oncogenic risk (hr-HPV); however, several cofactors are important in its carcinogenesis, such as smoking, multiparity, and prolonged use of oral hormonal contraceptives (COCs). Worldwide, 16% of women use COCs, whereas in Brazil this rate is of ∼ 30%. The safety and adverse effects of COCs are widely discussed in the literature, including the increase in carcinogenic risk. Due to the existence of several drugs, combinations, and dosages of COCs, it is hard to have uniform information in epidemiological studies. Our objective was to perform a narrative review on the role of COCs use in the carcinogenesis of cervical cancer. Several populational studies have suggested an increase in the incidence of cervical cancer for those who have used COCs for > 5 years, but other available studies reach controversial and …
引用总数
学术搜索中的文章
AC Bovo, PG Pedrão, YM Guimarães, LR Godoy… - Revista Brasileira de Ginecologia e Obstetrícia/RBGO …, 2023