作者
Patrizia De Marco, Elisa Merello, Maria Grazia Calevo, Samantha Mascelli, Daniela Pastorino, Lucia Crocetti, Pierangela De Biasio, Gianluca Piatelli, Armando Cama, Valeria Capra
发表日期
2011/7
期刊
Child's Nervous System
卷号
27
页码范围
1073-1081
出版商
Springer-Verlag
简介
Purpose
Neural tube defects, including spina bifida and anencephaly, are the second most common birth defects with an incidence in Italy of 0.4–1/1,000. Information on factors playing a role in the pathogenesis of spina bifida is based on populations with different exposures, lifestyle, social and cultural habits compared to Italian people. Our objective was to fill this gap by using data from a case–control interview study carried out at the G. Gaslini Children’s Hospital, Genoa, from 2000 to 2008.
Methods
We surveyed questionnaires from 133 case mothers and 273 control women providing information on periconceptional risk factors. Univariate and multivariate logistic regression analyses were used to estimate risks by odds ratios (ORs) and 95% confidence intervals (95% CIs).
Results
Univariate results suggest that birth …
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