作者
Claudio Da Cunha, Alexander Gomez-A, Charles D Blaha
发表日期
2012/11/1
来源
Reviews in the Neurosciences
卷号
23
期号
5-6
页码范围
747-767
出版商
De Gruyter
简介
The present paper reviews foundational and contemporary theories of motivated behaviors and the growing body of evidence that they require specific functional interactions within the basal ganglia. Such evidence suggests that unconditioned responses (UR), conditioned responses (CR), goal-directed actions and stimulus-response (S-R) habits are selected in the basal ganglia. Such selection depends on activation of striatal neurons by cortical and subcortical neurons encoding unconditioned stimuli (US), conditioned stimuli (CS), goals and neutral stimuli (S). These neurons project respectively to the medial nucleus accumbens (NAc) shell/olfactory tubercle, NAc core/lateral olfactory tubercle, dorsolateral striatum and dorsomedial striatum. The strength of these synapses is altered when the levels of extracellular dopamine in the basal ganglia undergo phasic increases or decreases, which signal outcomes that …
引用总数
201220132014201520162017201820192020202120222023202412417968816681
学术搜索中的文章
C Da Cunha, A Gomez-A, CD Blaha - Reviews in the Neurosciences, 2012