作者
BS Wang, A Narayanaswamy, N Amerasinghe, C Zheng, M He, YH Chan, ME Nongpiur, DS Friedman, Tin Aung
发表日期
2011/1/1
期刊
British Journal of Ophthalmology
卷号
95
期号
1
页码范围
46-50
出版商
BMJ Publishing Group Ltd
简介
Aims
To investigate the relationship between quantitative iris parameters and angle closure disease.
Methods
Participants with angle closure were recruited prospectively from glaucoma clinics. Anterior segment optical coherence tomography (AS-OCT) was performed under standardised dark conditions. Customised software was used on horizontal AS-OCT scans to measure iris thickness at 750 um (IT750) and 2000 um (IT2000) from the sclera spur, maximal iris thickness (ITM) and cross-sectional area of the iris (I-Area).
Results
167 Angle closure (consisting of 50 primary angle-closure (PAC), 73 primary angle closure glaucoma (PACG) and 44 fellow eyes of acute PAC) and 1153 normal participants were examined. After adjusting for age, sex, pupil size and anterior chamber depth, mean IT750 (0.499 vs 0.451 mm, p<0.001), IT2000 (0.543 vs 0.479 mm, p<0.001), ITM (0.660 vs 0.602 mm, p<0.001) and I-Area …
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