作者
Kyle Scholten, Patrick Twohig, Kaeli Samson, Kevin Brittan, Alexandra Fiedler, Josh Warner, Tomoki Sempokuya, Anna Willet, Marco Olivera
发表日期
2024/3/1
期刊
Digestive and Liver Disease
出版商
WB Saunders
简介
Background
Serum phosphatidylethanol (PEth) testing has emerged as a promising biomarker for assessing recent alcohol consumption, surpassing the limitations of self-reported data. Limited clinical data exists comparing PEth levels and patients' reported alcohol intake.
Aims
Compare PEth testing results with self-reported alcohol intake and assesses variables associated with underreporting.
Methods
Single-center retrospective cohort of patients with a diagnosis of chronic liver disease and serum PEth. A patient's first positive PEth (>/=10 ng/mL) and self-reported alcohol consumption was used. PEth results were categorized as mild (10–20), moderate (20–200), or heavy (>200). Severity measures between self-report and PEth were assessed using Bhapkar's test and Bonferroni-adjusted McNemar's tests. Demographic data was analyzed using Chi-Square tests.
Results
279 patients were included. 94 (33.7 …
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