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We address the problem of segmenting a sequence of images of natural scenes into disjoint regions that are characterized by constant spatio-temporal statistics. We model the spatio-temporal dynamics in each region by Gauss-Markov models, and infer the model parameters as well as the boundary of the regions in a variational optimization framework. Numerical results demonstrate that - in contrast to purely texture-based segmentation schemes - our method is effective in segmenting regions that differ in their dynamics even when spatial statistics are identical.