作者
Mert Ocak, Şükrü Ateş, Selda Kahveci, Aslı Okan, Züleyha Doğanyiğit, Sümeyye Uçar, Seher Yılmaz
发表日期
2024/3/25
期刊
Asia‐Pacific Journal of Clinical Oncology
简介
Background
Studies for new treatment strategies on cancer continue, and new searches continue in the diagnosis and evaluation of cancer. This study examined the possible anticarcinogenic effect of Rutin on the brain tissues of male mice with Ehrlich ascites carcinoma (EAC).
Material and methods
We used micro‐computed tomography (micro‐CT) and histologically Hematoxylin&Eosin (H&E) staining methods for evaluation.
Results
In the evaluation results, we saw a significant decrease in the brain volume of the tumor group to the control group. The difference in volume between the Rutin treatment group and the control group was not significant. In the brain tissues of the tumor group, numerous degenerated neurons characterized by pericellular/perivascular space expansion, cell swelling, or expansion were detected in the cortex and hippocampus regions. We showed a reduction in the damage rate in the …
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