作者
Alexander KC Leung, KL Hon, KF Leong, CM Sergi
发表日期
2018/10/1
来源
Hong Kong Medical Journal
卷号
24
期号
5
页码范围
512
出版商
Hong Kong Academy of Medicine
简介
Measles (rubeola) is a highly contagious vaccinepreventable disease caused by the measles virus—a virus of the Paramyxoviridae family. The illness typically begins with fever, runny nose, cough, and pathognomonic enanthem (Koplik spots) followed by a characteristic erythematous, maculopapular rash. The rash classically begins on the face and becomes more confluent as it spreads cephalocaudally. Laboratory confirmation of measles virus infection can be based on a positive serological test for measles-specific immunoglobulin M antibody, a four-fold or greater increase in measles-specific immunoglobulin G between acute and convalescent sera, isolation of measles virus in culture, or detection of measles virus ribonucleic acid by reverse transcriptase-polymerase chain reaction. Complications occur in 10% to 40% of patients, and treatment is mainly symptomatic. Bacterial superinfections, if present, should be properly treated with antibiotics. To eradicate measles, universal childhood immunisation and vaccination of all susceptible individuals with measles vaccine would be ideal. In developed countries, routine immunisation with measles-containing vaccine is
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学术搜索中的文章
AKC Leung, KL Hon, KF Leong, CM Sergi - Hong Kong Medical Journal, 2018