作者
France Denoeud, Simon Henriet, Sutada Mungpakdee, Jean-Marc Aury, Corinne Da Silva, Henner Brinkmann, Jana Mikhaleva, Lisbeth Charlotte Olsen, Claire Jubin, Cristian Cañestro, Jean-Marie Bouquet, Gemma Danks, Julie Poulain, Coen Campsteijn, Marcin Adamski, Ismael Cross, Fekadu Yadetie, Matthieu Muffato, Alexandra Louis, Stephen Butcher, Georgia Tsagkogeorga, Anke Konrad, Sarabdeep Singh, Marit Flo Jensen, Evelyne Huynh Cong, Helen Eikeseth-Otteraa, Benjamin Noel, Véronique Anthouard, Betina M Porcel, Rym Kachouri-Lafond, Atsuo Nishino, Matteo Ugolini, Pascal Chourrout, Hiroki Nishida, Rein Aasland, Snehalata Huzurbazar, Eric Westhof, Frédéric Delsuc, Hans Lehrach, Richard Reinhardt, Jean Weissenbach, Scott W Roy, François Artiguenave, John H Postlethwait, J Robert Manak, Eric M Thompson, Olivier Jaillon, Louis Du Pasquier, Pierre Boudinot, David A Liberles, Jean-Nicolas Volff, Herve Philippe, Boris Lenhard, Hugues Roest Crollius, Patrick Wincker, Daniel Chourrout
发表日期
2010/12/3
期刊
Science
卷号
330
期号
6009
页码范围
1381-1385
出版商
American Association for the Advancement of Science
简介
Genomes of animals as different as sponges and humans show conservation of global architecture. Here we show that multiple genomic features including transposon diversity, developmental gene repertoire, physical gene order, and intron-exon organization are shattered in the tunicate Oikopleura, belonging to the sister group of vertebrates and retaining chordate morphology. Ancestral architecture of animal genomes can be deeply modified and may therefore be largely nonadaptive. This rapidly evolving animal lineage thus offers unique perspectives on the level of genome plasticity. It also illuminates issues as fundamental as the mechanisms of intron gain.
学术搜索中的文章
F Denoeud, S Henriet, S Mungpakdee, JM Aury… - Science, 2010