作者
Jack V Tu, James Bowen, Maria Chiu, Dennis T Ko, Peter C Austin, Yaohua He, Robert Hopkins, Jean-Eric Tarride, Gord Blackhouse, Charles Lazzam, Eric A Cohen, Ron Goeree
发表日期
2007/10/4
期刊
New England Journal of Medicine
卷号
357
期号
14
页码范围
1393-1402
出版商
Massachusetts Medical Society
简介
Background
The placement of drug-eluting stents decreases the frequency of repeat revascularization procedures in patients undergoing percutaneous coronary intervention (PCI) in randomized clinical trials. However, there is uncertainty about the effectiveness of drug-eluting stents, and increasing concern about their safety, in routine clinical practice.
Methods
From the Cardiac Care Network of Ontario's population-based clinical registry of all patients undergoing PCI in Ontario, Canada, we identified a well-balanced cohort of 3751 pairs of patients, matched on the basis of propensity score, who received either bare-metal stents alone or drug-eluting stents alone during an index PCI procedure between December 1, 2003, and March 31, 2005. The primary outcomes of the study were the rates of target-vessel revascularization, myocardial infarction, and death.
Results
The 2-year rate of target-vessel …
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