作者
Pontus Andell, Karolina Berntorp, Evald H Christiansen, Ingibjörg J Gudmundsdottir, Lennart Sandhall, Dimitrios Venetsanos, David Erlinge, Ole Fröbert, Sasha Koul, Christian Reitan, Matthias Götberg
发表日期
2018/10/22
期刊
JACC: Cardiovascular Interventions
卷号
11
期号
20
页码范围
2084-2094
出版商
American College of Cardiology Foundation
简介
Objectives
The authors sought to compare reclassification of treatment strategy following instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR).
Background
iFR was noninferior to FFR in 2 large randomized controlled trials in guiding coronary revascularization. Reclassification of treatment strategy by FFR is well-studied, but similar reports on iFR are lacking.
Methods
The iFR-SWEDEHEART (Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve in Patients With Stable Angina Pectoris or Acute Coronary Syndrome Trial) study randomized 2,037 participants with stable angina or acute coronary syndrome to treatment guided by iFR or FFR. Interventionalists entered the preferred treatment (optimal medical therapy [OMT], percutaneous coronary intervention [PCI], or coronary artery bypass grafting [CABG]) on the basis of coronary angiograms, and the final treatment decision was mandated by …
引用总数
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