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Background: His bundle pacing (HBP) can correct left bundle branch block (LBBB) allowing QRS normalization and correction of ventricular dyssynchrony. Objective: Aim of the present study was to analyze technical and clinical outcomes of HBP in LBBB patients referred for PM implantation with preserved ejection fraction (EF).

Methods: 36 patients (75±8 years; 17 males) presenting LBBB (mean QRS duration 163±23 ms) received permanent HBP. Indications for pacing were AV block (25 pts; 70%), sinus node disease (8 pts; 22%), AF with slow ventricular rate (3 pts; 8%). A back up lead was implanted in RV apex in 15 (42%) patients. 5 (14%) pts had ischemic cardiomyopathy, 30 (83%) pts had hypertension, 6 (17%) pts had diabetes, and 2 (5%) pts had severe kidney disease. 4 (16%) pts had permanent AF. Basal mean EF was 53±11%. Mean NYHA class was 1, 7±0, 7. Results: In 32 patients (89%) we obtained …