作者
AM Alavi Naeini, I Elmadfa, A Djazayery, M Barekatain, MR Aghaye Ghazvini, M Djalali, A Feizi
发表日期
2014/8
期刊
European journal of nutrition
卷号
53
页码范围
1255-1262
出版商
Springer Berlin Heidelberg
简介
Purpose
This study was carried out to investigate the effect of vitamins E and C on cognitive performance among the elderly in Iran.
Methods
About 256 elderly with mild cognitive impairment, aged 60–75 years, received 300 mg of vitamin E plus 400 mg of vitamin C or placebo daily just for 1 year.
Background
Demographic characteristics, anthropometric variables food consumption, cognitive function by Mini-Mental State Examination (MMSE), and some of the oxidative stress biomarkers were examined.
Results
Antioxidant supplementation reduced malondialdehyde level (P < 0.001) and raised total antioxidant capacity (P < 0.001) and glutathione (P < 0.01). The serum 8-hydroxydeoxyguanosine remained unchanged (P < 0.4). After adjusting for the covariates effects, MMSE scores …
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AM Alavi Naeini, I Elmadfa, A Djazayery, M Barekatain… - European journal of nutrition, 2014