作者
Dong Yeon Park, Dennis Do, Lauren Chang, Saloni Shah, Laura D Yuen, Farnaz Hooshmand, Po W Wang, Shefali Miller, Terence A Ketter
发表日期
2018/2/1
期刊
Journal of Affective Disorders
卷号
227
页码范围
657-664
出版商
Elsevier
简介
Aims
Assess episode accumulation (≥ 10 prior mood episodes) associations with demographic/baseline clinical characteristics and mood episode recurrence/recovery in bipolar disorder (BD).
Methods
Stanford BD Clinic outpatients enrolled during 2000–2011 were assessed with Systematic Treatment Enhancement Program for BD (STEP-BD) Affective Disorders Evaluation. Among recovered and syndromal mood episode patients, we assessed episode accumulation associations with demographic/baseline clinical characteristics and with recurrence/recovery (by Kaplan-Meier survival analyses, with mediators assessed with Cox Proportional Hazard Ratio (HR) analyses).
Results
Among all 450 BD outpatients, almost twice as many had versus lacked episode accumulation (65.8% versus 34.2%), which was less common among 92 recovered versus 193 syndromal mood episode patients (51.1% versus 69.9 …
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DY Park, D Do, L Chang, S Shah, LD Yuen… - Journal of Affective Disorders, 2018