作者
Francisco Blanco-Vaca, Lídia Cedó, Josep Julve
发表日期
2019/11/1
来源
Current Medicinal Chemistry
卷号
26
期号
37
页码范围
6735-6749
出版商
Bentham Science Publishers
简介
Cancer is the second leading cause of death worldwide. Compelling evidence supports the hypothesis that the manipulation of dietary components, including plant compounds termed as phytochemicals, demonstrates certain important health benefits in humans, including those in cancer. In fact, beyond their well-known cardiovascular applications, phytosterols may also possess anticancer properties, as has been demonstrated by several studies. Although the mechanism of action by which phytosterols (and derivatives) may prevent cancer development is still under investigation, data from multiple experimental studies support the hypothesis that they may modulate proliferation and apoptosis of tumor cells. Phytosterols are generally considered safe for human consumption and may also be added to a broad spectrum of food matrices; further, they could be used in primary and secondary prevention. However, few …
学术搜索中的文章
F Blanco-Vaca, L Cedó, J Julve - Current Medicinal Chemistry, 2019