作者
Vijay Kunadian, Gary A Ford, Bilal Bawamia, Weiliang Qiu, JoAnn E Manson
发表日期
2014/3/1
来源
American heart journal
卷号
167
期号
3
页码范围
283-291
出版商
Mosby
简介
Coronary artery disease remains the leading cause of death in developed countries despite significant progress in primary prevention and treatment strategies. Older patients are at particularly high risk of poor outcomes following acute coronary syndrome and impaired nutrition, including low vitamin D levels, may play a role. The extraskeletal effects of vitamin D, in particular, its role in maintaining a healthy cardiovascular system are receiving increased attention. Longitudinal studies have demonstrated increased cardiovascular mortality and morbidity associated with vitamin D deficiency. Low vitamin D levels have been linked to inflammation, higher coronary artery calcium scores, impaired endothelial function and increased vascular stiffness. However, so far, few randomized controlled trials have investigated the potential benefits of vitamin D supplementation in preventing cardiovascular events, and most …
引用总数
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学术搜索中的文章
V Kunadian, GA Ford, B Bawamia, W Qiu, JAE Manson - American heart journal, 2014