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Aim: Postprandial changes acutely alter some mechanisms in body. There are many studies showing blood oxidative status changes after food intake and supplementation. The aim of the present study was to evaluate the effects of a standardized meal on serum total antioxidant activity (TAA) in normal weight and overweight individuals. Material and Method: Fourteen normal weight and twelve overweight individuals were given a standardized meal in the morning after an overnight fast. Serum TAA, glucose, total cholesterol, HDL cholesterol, LDL cholesterol and triglyceride concentrations were measured at baseline, 3rd hour and 6th hour after the meal in both groups. Results: In both normal and overweight groups, the difference between baseline and 3rd hour was significant for TAA. The TAA of the overweight group was also significantly lower than the TAA of the normal weight group at 3rd hour. However, there …